jrohilayushRohilkhand Journal of AYUSH ResearchCoRJAR 2025 Vol. I Issue IMultidisciplinaryEnglishMarch -September 2025NNY2025091Ayurveda Swarna Bhasma: Repurposing Ayurvedic Gold Nanoparticles for Blinding Ocular DiseasesEnglishY1520style="font-family:CalibriEnglishNsans-serif">Roman"EnglishYserif">Shimi Ben. C.J.1*EnglishYhttps://doi.org/10.65001/RJAR.2025.V1I103The convergence of traditional medicine and modern nanotechnology offers a promising frontier for developing novel therapeutics. Swarna Bhasma (SB), a calcined gold ash used in Ayurvedic medicine for centuries, is a quintessential example of an innate nanomaterial. Recent characterization studies have confirmed that SB consists of spherical and crystalline gold nanoparticles (AuNPs) in a size range (10-80 nm) ideal for biomedical applications. This review article suggests Swarna Bhasma as a potent tool for nanotechnology-based interventions in Ophthalmology by exploring its physicochemical properties, including its nanoscale dimension, bioavailability, and unique biological activities such as anti-angiogenic, anti-inflammatory, and antioxidant effects. Also, propose the mechanistic pathways through which these properties can target the pathophysiological underpinnings of major eye diseases, including Age-related Macular Degeneration (ARMD), Diabetic retinopathy, Cataracts, and Uveitis. The article concludes by discussing the challenges and future directions for translating this ancient nanomedicine into a standardized, evidence-based therapeutic agent for modern ophthalmic practice, highlighting its potential for targeted, safe, and multi-factorial treatment of complex ocular pathologies.EnglishSwarna Bhasma, Ayurveda, Nanomedicine, Gold Nanoparticles, Ophthalmology, Age-Related Macular Degeneration, Diabetic Retinopathy, Ocular Drug Delivery, Rasayanahttps://www.jrohilayush.com/abstract?id=2References1619